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A 38-year-old man referred from the department of psychiatry for sudden appearance of extensive skin lesions... What's your diagnosis ?
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Fixed Drug Eruption (FDE)
FDEs
are usually characterized by a single or a few, sharply demarcated
erythematous lesions, but in the most severe form of FDE called
“Generalized Bullous Fixed Drug Eruption” (GBFDE), there are
symmetric multiple large purplish-livid patches with predilection
for the acral extremities and genital areas and usually with sparing
the mucosal sites. If widely extensive or close to erythrodermic, it
can be easily mistaken for one of the subsets of TEN or
Stevens-Johnson syndrome. Absence of constitutional symptoms and
rapid recovery without scarring usually help in differentiating GFDE
from similar conditions.
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